How Many 500 mg Amoxicillin Should You Take a Day? Amoxicillin 500 mg is a widely prescribed antibiotic used to treat various bacterial infections, including respiratory tract infections, ear and urinary tract infections, skin infections, and more Mayo ClinicMedlinePlus. Typical Adult Dosage: Every 8 hours (three times a day) — i.e., 500 mg taken at 8-hour intervals Or every 12 hours (twice a day) — i.e., 500 mg taken at 12-hour intervals These schedules depend on the type and severity of the infection Mayo ClinicMedlinePlus. Important Note: Always follow your doctor's instructions. Do not self-medicate with antibiotics, as misuse can lead to incomplete treatment or antibiotic resistance. #Amoxicillin #AntibioticDosage #SafeMedicineUse #DoctorAdvice #AntibioticResistance